Day 1 – Wednesday, January 19, 2022
Mechanisms of Resistance and Drug Discovery
7:30 – 8:20 Career Mentoring: Clinical Scientist Pathway
Barbara Trautner, MD, PhD
Baylor College of Medicine, Houston, TX
Anthony Flores, MD, PhD
University of Texas Health Science Center, Houston, TX.
Sam Shelburne, MD, PhD
UT MD Anderson Cancer Center, Houston, TX
8:30 – 8:40 GCC Welcome
Suzanne Tomlinson, PhD, MBA
Gulf Coast Consortia
8:40 – 8:45 Welcome
Cesar A. Arias, MD, PhD
Houston Methodist Hospital and Weill Cornell Medical College
8:45 – 9:10 ARLG and the Future of Clinical Research in Antimicrobial Resistance
Vance Fowler, MD, MPH
Duke University, Durham, NC
Session 1
Conveners: Julian Hurdle, PhD, Texas A&M Health Science Center
William Miller, MD, Houston Methodist Hospital and Weill Cornell Medical College
9:10 – 9:35 Cell Division in Gram-positive cocci
Mariana Gomes de Pinho, PhD
University of Lisbon, Lisbon, Portugal
9:35 – 10:00 The Ribosome as an Antimicrobial Target
Alexander Mankin, PhD
University of Illinois, Chicago, IL
10:00 – 10:25 Fluoroquinolones, Topoisomerases, and Supercoiled DNA
Lynn Zechiedrich, PhD
Baylor College of Medicine, Houston, TX
10:25 – 10:55 Vendor Show and Networking
Session 2 T32 Trainee Symposium: Texas Medical Center Training Program on Antimicrobial Resistance (TP-AMR), Emory Training Program on Antimicrobial Resistance, University of Pittsburgh Training Program on Antimicrobial Resistance
Conveners: Shantanu Guha, PhD, MPH
University of Texas Health Science Center at Houston, Houston, TX
Edwin Chen, PhD, University of Pittsburgh, Pittsburgh, PA
10:55 – 11:10 Discovery of Inhibitors of Antimicrobial Resistance Enzymes Using a Focused DNA-Encoded Library
Suhyeorn “Jane” Park
Baylor College of Medicine, Houston, TX
11:10 – 11:25 Exploration of a Synthetic Retinoid Scaffold for the Treatment of Persistent MRSA Infections
Cassandra Schrank
Emory University, Atlanta, GA
11:25 – 11:40 Pareto Optimality Fronts Model as a Tool for Understanding Evolutionary Tradeoffs of Antibiotic Resistance
Francine Arroyo, PhD
University of Pittsburgh, Pittsburgh, PA
Convener: Lynn Zechiedrich, PhD
Baylor College of Medicine, Houston, TX
11:40 – 12:20 Key Note Lecture
Is Phage Therapy Here to Stay?
Paul Turner, PhD
Yale University, New Haven, CT
12:20-12:40 Lunch
12:40-1:10 Rapid Fire
Saoirse Disney-McKeethen, Rice Univ.
Thomas Horvath, Baylor College of Medicine
Firas Said Midani, Baylor College of Medicine
April Nguyen, University of Texas Health Science Center
Zhizeng Sun, Baylor College of Medicine
Adeline Supandy, Rice University
1:10 -2:00 Poster Presentations
Session 3
Conveners: Tim Palzkill, PhD, Baylor College of Medicine
Cecilia Tran, PharmD, Houston Methodist Research Institute
2:00 – 2:25 Carbapenemases in the 21st Century
Jim Spencer, PhD
University of Bristol, United Kingdom
2:25 – 2:50 Antibiotic Resistance in Emergent Pathogens Ashok Chopra, PhD
University of Texas Medical Branch, Galveston, TX
2:50 – 3:15 Microfluidic Technology to Study Bacterial Evolution to Antibiotics
Yousif Shamoo, Phd
Rice University, Houston, TX
3:15 – 3:30 Break
Session 4 NIH Antimicrobial Resistance Leadership Group (ARLG) Early Stage Investigators
Conveners: Anthony Harris, MD MPH, University of Maryland, Baltimore, MD
Henry Chambers MD, University of California, San Francisco, CA
3:30 – 3:45 DOOR Analysis and cUTI
Jessica Howard-Anderson, MD
Emory University, Atlanta, GA
3:45 – 4:00 DOOR Endpoint Analysis in Intraabdominal Infection: FDA-NIH Collaboration
Air Force 2nd Lt. Tori Kinamon
Duke University, Durham, NC
4:00 – 4:15 DOTS Trial: Dalbavancin as an Option for Treatment of Staphylococcus aureus Bacteremia
Nicolas Turner, MD
Duke University, Durham, NC
4:15 – 4:30 PHAGE Trial
Maria Souli, MD
Duke University, Durham, NC
Session 5 Selected Abstracts
Convener: Sam Shelburne, MD, PhD, UT MD Anderson Cancer Center, Houston, TX
Natasha Kirienko, PhD, Rice University, Houston, TX
4:30 – 4:45 Peptidoglycan Recycling Contributes to Outer Membrane Integrity and Carbapenem Tolerance in Acinetobacter baumannii
Nowrosh Islam, UT Arlington
4:45 – 5:00 Anatomy of an Extensively Drug Resistant Klebsiella pneumoniae Outbreak in Tuscany, Italy
Melissa Martin, PhD
Walter Reed Army Institute of Research
5:00 – 5:15 Combination Eravacycline Therapy for Carbapenem-Resistant Acinetobacter baumannii Pneumonia
Melissa Jackson, PharmD
Parkland Health & Hospital System
Day 2 – Thursday, January 20, 2022
Translational and Clinical Aspects of Antibiotic Resistance
7:30 – 8:20 Career Mentoring: PharmD Translational/Clinical Scientist Pathway
Cecilia Tran, PharmD
Houston Methodist Research Institute, Houston, TX
William Musick, PharmD
Houston Methodist Hospital, Houston, TX
Vincent Tam, PharmD
University of Houston, Houston, TX
Session 6
Conveners: Blake Hanson, PhD, University of Texas Health Science Center, Houston, TX
Vincent Tam, PharmD, University of Houston, Houston, TX
8:30 – 8:55 Combination Therapies for Gram-negative Bacteria David van Duin, MD PhD
University of North Carolina, Durham, NC
8:55 – 9:20 Combination Therapies for Gram-positive Bacteria
George Sakoulas, MD
University of California, San Diego, CA
9:20 – 9:45 Combined Genotypic and Phenotypic Antibiotic Susceptibility Testing Through Gene Expression Profiling
Roby Bhattacharyya, MD PhD
Massachusetts General Hospital and Broad Institute, Harvard University, Boston, MA
9:45 – 9:55 Vendor Show: Gold Vendor
Rapid Diagnostics and the Impact on Sepsis
John Sperzel
T2 Biosystems
9:55-10:15 Break
Session 7 T32 Trainee Symposium: Texas Medical Center Training Program on Antimicrobial Resistance (TP-AMR), Emory Training Program on Antimicrobial Resistance, University of Pittsburgh Training Program on Antimicrobial Resistance
Conveners: Cassandra Schrank, Emory University, Atlanta, GA
10:15 – 10:30 Microbial Therapeutics as Antibiotic Alternative to Suppress Gastrointestinal Pathogen Growth
Eva Preisner, PhD
Baylor College of Medicine, Houston TX
10:30 – 10:45 Lost in Translation: Developing Novel Antibiotics Against Bacterial Ribosome Rescue
Pooja Srinivas
Emory University, Atlanta, GA
10:45 – 11:00 Development of Novel Antifungals Against Candida Based on an Antifungal Peptide Produced by E. faecalis
Shantanu Guha, PhD, MPH
University of Texas Health Science Center, Houston, TX
11:00 – 11:15 Mutations that Inactivate the Tricarboxylic Acid Cycle in Staphylococcus aureus Arise During Persistent MRSA Bacteremia
Edwin Chen PhD
University of Pittsburgh, Pittsburgh, PA
11:15 – 11:30 An Epidemiologic Exploration of Vancomycin Resistance in Clostridioides difficile
Taryn Eubank, PharmD
University of Houston, Houston, TX
11:30 – 12:10 Key Note Lecture
Tigers by The tail: Integrated Analyses of Emerging Infectious Diseases
James Musser, MD, PhD
Houston Methodist Hospital and Weill Cornell Medical College, Houston, TX
12:10-12:30 Lunch
12:30-1:05 Rapid Fire
Lorena Diaz, Universidad El Bosque
Jesus Duran Ramirez, University of Texas Health Science Center
Stephanie Egge, University of Texas Health Science Center
Sara Gomez-Villegas, Houston Methodist Research Institute
Thanh Le, University of Houston
Daniel Stanton, University of Texas Medical Branch
Liyang Zhang, Rice University
1:05-2:00 Poster Presentations
Session 8
Conveners: Cesar A. Arias MD, PhD
Houston Methodist Hospital and Weill Cornell Medical College, Houston, TX
2:00 – 3:00 Challenging Clinical Cases in Antimicrobial Resistance
Samuel Shelburne, MD, PhD
UT MD Anderson Cancer Center, Houston, TX
David van Duin, MD PhD
University of North Carolina, Durham, NC
William Miller, MD
Houston Methodist Hospital and Weill Cornell Medical College, Houston, TX
Session 9 ARLG Session 2
Understanding the Enemy: Clinical and Microbiological Characterization of MDR Gram Negative Bacteria
Conveners: Vance Fowler, MD, MPH, Duke University, Durham, NC
Helen Boucher MD, Tufts University, Boston, MA
3:00 – 3:15 Characterization of MDRO in South America
Jinnethe Reyes, PhD
Universidad El Bosque, Bogota, Colombia
3:15 – 3:30 SNAP International
Yohei Doi, MD, PhD
University of Pittsburgh, Pittsburgh, PA
3:30 – 3:45 POP International
Mike Satlin, MD
Weill Cornell Medical College, New York, NY
3:45 – 4:00 SHREC
David van Duin, MD, PhD
University of North Carolina, Durham, NC
4:00 – 4:30 Vendor Show and Networking
Session 10
Conveners: Tor Savidge, PhD, Baylor College of Medicine, Houston, TX
Todd Treangen, PhD, Rice University, Houston, TX
4:30 – 4:55 Emerging Fungal Diseases and Resistance
Mihalis Lionakis, MD
NIAID, Bethesda, MD
4:55 – 5:20 New Antifungals
Dimitrios Kontoyannis, MD
UT MD Anderson Cancer Center, Houston, TX
5:20 – 5:45 An Update on β-lactamase Inhibitors
Karen Bush, PhD
University of Indiana, Bloomington, IN
Day 3 – Friday, January 21, 2021
Antibiotic Stewardship
7:30 – 8:20 Careers in Clinical Microbiology
Micah Bhatti, MD, PhD
UT MD Anderson Cancer Center, Houston, TX
Wesley Long MD, PhD
Houston Methodist Hospital and Weill Cornell Medical College, Houston, TX
Audrey Wanger, PhD
University of Texas Health Science Center, Houston, TX
Session 11
Conveners: Ed Septimus, MD
Harvard Medical School and Texas A&M College of Medicine, Houston, TX
Kevin Garey, PharmD
University of Houston, Houston, TX.
8:30 – 8:35 Welcome
Ed Septimus, MD
Harvard Medical School and Texas A&M College of Medicine, Houston, TX
8:35 – 9:05 Keynote
Dissecting Epidemics of Multidrug-resistant Organisms
Cesar A. Arias, MD, PhD
Houston Methodist Hospital and Weill Cornell Medical College, Houston, TX
9:05 – 9:30 Pharmacokinetic/Pharmacodynamics of Antibiotics in Renal Replacement Therapies
Bruce Mueller, PharmD
University of Michigan, Ann Harbor, MI
9:30 – 9:55 The INSPIRE Trial
Shruti Gohil, MD, MPH
University of California, Irvine, CA
9:55 – 10:25 Vendor show and networking
Session 12
Conveners: Kristi Kuper, PharmD
Tabula Rasa HealthCare/DoseMeRx
10:25 – 10:50 Making the Cut: Antimicrobial Stewardship in Surgery
Rachel Britt, PharmD
University of Texas Medical Branch, Galveston, TX
10:50 – 11:15 Impact of the Pandemic on Antimicrobial Resistance Priya Nori, MD
Albert Einsten College of Medicine, Bronx, NY
11:15 – 11:40 An Update on the Management of Clostridiodes difficile Infections
Kevin Garey, PharmD
University of Houston, Houston, TX
11:40-12:00 Lunch
12:00-12:30 Rapid Fire
Andrew Chou, Michael E DeBakey VA Medical Center/Baylor College of Medicine
Sabrina Green, Baylor College of Medicine
Larissa Grigoryan, Baylor College of Medicine
Lindsey Laytner, Baylor College of Medicine
Timothy Straub, SERES Therapeutics
Marissa Valentine-King, Baylor College of Medicine
12:30 -1:20 Poster Presentations
1:20 – 1:50 Panel Discussion: Nursing Homes Response to COVID-19: Lessons Learned
Charlene Evans Offiong, PharmD
Houston Health Department
Oluwayemisi Aikulola, MD, MPH
Houston Health Department
Catherine Anglin
Texas Health and Human Services
Abisola Oladimeji, MD, MPH
Bureau of Epidemiology, Houston Health Department
Tolu Olumuyiwa, MPH
Houston Health Department
Shawn Tupy, MT, MBA
Texas DSHS
Vijisha C Vijayan, BDS, MPH
Houston Health Department
Session 13
Conveners: Robert Atmar, MD, Baylor College of Medicine, Houston, TX
1:50 – 2:15 Antifungal Susceptibility Testing of Molds: When, Why, and How
Nathan Wiederhold, PharmD
University of Texas San Antonio
2:15 – 2:40 Harvard Medical Schoo
lMonica Mahoney, PharmD
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
2:40 – 3:05 An Update on COVID-19 Vaccines
Hana El Sahy, MD
Baylor College of Medicine, Houston, TX.
3:05 Closing remarks